Clinical Research Department

  • INTRODUCTION
  • FACULTY AND STAFF
  • ACHIEVEMENTS
  • ETHICAL RESEARCH COMMITTEE (ERC)
  • LIST OF PUBLICATIONS

Research carries fundamental significance for the identification of problems, development of clinical applications from concepts, their administration, and thus making subsequent progressive improvements for patients' services and of course highlighting recommendation for future research.
The field of cardiovascular diseases demands research applied to clinical practice more than any other. It would not be far from being consonant with the true facts, that the most successful stage where the entire span of cardiac medicine and surgical specialties stand today, are the most vivid proof of the outcome of clinical research.

Till now there was no formal set-up in tertiary care hospital settings in the entire public sector where the needs of the research oriented clinical practice could be provided for, or from where research could be initiated on issues involved.

NICVD being an apex institution in the fields of cardiac care, bearing a national outlook and character, has now reached a stage of development where clinical research is being formalized in the form of a fully-fledged Clinical Research department. Since its establishment in 1963 NICVD is the leading center for Postgraduate training in Adult cardiac medicine, Pediatric Cardiology, Anesthesiology and Cardiac Surgery both for Adult and Paeds.

The primary objective of Clinical Research department is to progressively develop a streamline system to facilitate and promote clinical research and provide a data warehouse with the capacity to convert data into actionable information and facilitate the development of systems, procedures, modalities to ensure progressively improving patient services, emergency care, training of health and allied professionals, and all other related issues required to ensure a better and progressive patient care. We also aim to coordinate with all such research units, health and public health institutions in the country and internationally.

The services of the unit, although emanating from NICVD will be open to all who would like to acquire support towards the objective of services for the society in the field of cardiac care and all related fields.
The department of Clinical Research welcomes all in the development and promotion of clinical research in the country, so that the outcome of cardiac care is progressively improved.

FACULTY AND STAFF

Director Research Dr. Tahir Saghir
Manager Research Shumaila Furnaz
Research Coordinator Dr. Sobia Masood
Statistician Moosa Karim

ACHIEVEMENTS

  • Participation in NCDR: 15,000 patients enrolled up till now
  • Participation in International Quality Improvement Collaborative (IQIC)
  • Congenital cardiac surgery data base from Children's School of Boston
  • Participation in European Society of Cardiology registries
  • Each year, Clinical Research Department celebrates "Research Day"
  • Paper: Current characteristics of infective endocarditis in a developing country: a prospective cohort study accepted for Annual Heart failure 2019 conference with free registration and 400 euro travel scholarship.

INTERNATIONAL PARTICIPATIONS

Presenter Topic Conference
Dr. Mahesh Kumar Batra Successfully managed dissection of right coronary sinus GulfPCR-GIM 2017
Dr. Mahesh Kumar Batra Assessment of Electrocardiographic Criteria of Left Atrial Enlargement 10th Annual Congress of Cardiology – 2018 (ICC-2018)
Dr. Sanam Khowaja Time to Think Beyond Door to Balloon Time: Significance of Total Ischemic Time in Patients with ST Elevation Myocardial Infarction American College of Cardiology's (ACC-2019) 68th Annual Scientific Session
Dr. Faisal Khanzada Frequency of Patients with Atherosclerotic Cardiovascular Disease Receiving High Intensity Statin Therapy and Types & Doses of Statin EuroPrevent 2019
Dr. Romana Awan Factors Leading to Poor Adherence to Secondary Prophylaxis of Rheumatic Fever EuroPrevent 2019
Shumaila Furnaz Factors Associated with Length of Hospital Stay in Patients with Endocarditis in a Developing Country Euro Heart Failure 2019

ETHICAL RESEARCH COMMITTEE (ERC)

MEMBERS
Dr. Tahir Saghir Dr. Zahid Jamal
Shumaila Furnaz Dr. Nawal Salahuddin
Dr. Zia Yaqub Dr. Khawar Kazmi
Download ERC Form
Download Consent Form

LIST OF PUBLICATIONS

Incidence of Cardiac Arrhythmias in Acute Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention and Associated Outcomes During the First 24 Hours

Jehangir A. Shah, Farah Naz, Rajesh Kumar, Muhammad Hassan, Ghazanfer Shah, Khalil Ahmed, Jamil Hussain, Khadijah Abid, Musa Karim

View Abstract View Article       Journal: Cureus       Year: 2021

Routine Measurement of Thyroid Stimulating Hormone in Patients Presenting With Third-Degree Atrioventricular Block: Do We Really Need It?

Muhammad Faisal, Zubair Mumtaz, Abdul Mueed, Sajid Ali, Haseeb H. Raza, Samra Khan, Sayeda Salma, Mustajab Mujtaba, Musa Karim, Faisal Qadir

View Abstract View Article       Journal: Cureus       Year: 2021

Pakistan Following Foot Prints of Developed World in Structural Interventions: Experience of Transcatheter Aortic Valve Implantation Reported First Time

Ali Ammar, Syed N. Hassan Rizvi, Tahir Saghir, Naveedullah Khan, Parveen Akhtar, Naeem Mengal, Jawaid A. Sial, Nadeem Qamar

View Abstract View Article       Journal: Cureus       Year: 2020

Psychosocial Impact of COVID-19 on Healthcare Workers at a Tertiary Care Cardiac Center of Karachi Pakistan

Dileep Kumar, Tahir Saghir, Gulzar Ali, Umamah Yasin, Shumaila Furnaz, Musa Karim, Muhammad Hussain, Rekha Kumari, Reeta Bai, Hitesh Kumar

View Abstract View Article       Journal: Journal of Occupational and Environmental Medicine       Year: 2020

Common Predisposing Factors in Mortality of Patients After Undergoing Mitral Valve Surgery at a Tertiary Care Hospital in Karachi

Zara Shirazi, Kashif Zia, Ali R. Mangi, Syed Minhaj, Vikram Utradi, Hafeezullah Bughio, Asmatullah Achakzai, Musa Karim, Fazal Rabbi, Pervaiz A. Chaudry

View Abstract View Article       Journal: Cureus       Year: 2020

Coronary Artery Anomalies in Tetralogy of Fallot Patients Undergoing CT Angiography at a Tertiary Care Hospital

Tariq Ashraf, Faiza Farooq, Afaque Syed Muhammad, Parveen Akhtar, Mubashir Khan, Amin M. Khuwaja, Muhammad N. Khan, Musa Karim

View Abstract View Article       Journal: Cureus       Year: 2020

Risk Factors Associated With Contrast-Induced Nephropathy after Primary Percutaneous Coronary Intervention

Dileep Kumar, Hussain Liaquat, Jawaid A. Sial, Tahir Saghir, Rekha Kumari, Hitesh Kumar, Musa Karim, Kelash Rai, Reeta Bai

View Abstract View Article       Journal: Cureus       Year: 2020

Prevalence of Cardiac Risk Factors and Attitude toward Self-Risk Assessment among Cardiac Care Givers

Shumaila Furnaz, Musa Karim, Sajjad Ali, Muhammad Tanzeel ul Haque, Muhammad Abdullah Usman, Dileep Kumar, Tariq Jamal Siddiqi, Khawar Abbas Kazmi

View Abstract View Article       Journal: Journal of Primary Care & Community Health       Year: 2020

Risk of Atherosclerotic Cardiovascular Diseases in various Ethnicities of Pakistan

Tariq Ashraf, Asif Nadeem, Shakil Sarwar, Musa Karim

View Abstract View Article       Journal: Pakistan Journal of Medical Sciences       Year: 2020

Antiplatelet Adherence at Six Months after Primary Percutaneous Coronary Intervention Performed At a Rural Satellite Center

Syed Fayaz Mujtaba, Javed Ur Rehman, Jawaid Akbar Sial, Riaz Ahmed Pathan, Musa Karim

View Abstract View Article       Journal: Pakistan Heart Journal       Year: 2020

Quality of life at six months after primary percutaneous coronary intervention performed at a predominantly rural population

Syed Fayaz Mujtaba, Jawaid Akbar Sial, Sajid Ali Shaikh, Muhammad Naeem, Imran Soomro, Musa Karim, Kiran Abbas, Moiz Ahmed, Kanza Abid Hussain

View Abstract View Article       Journal: International Journal of Advances in Medicine       Year: 2020

Depression and Anxiety in patients undergoing Percutaneous Coronary Intervention for Acute Coronary Syndrome

Syed Fayaz Mujtaba, Jawaid Akbar Sial, Musa Karim

View Abstract View Article       Journal: Pakistan Journal of Medical Sciences       Year: 2020

Differences in Angiographic Profile and Immediate Outcome of Primary Percutaneous Coronary Intervention in Otherwise Risk-Free Young Male Smokers

Salik Ahmed, Sanam Khowaja, Saher Khowaja, Tariq Ashraf, Kanwal Aamir, Mahesh K. Batra, Musa Karim, Muhammad Anis M. Ahmedani, Syed Z. Jamal

View Abstract View Article       Journal: Cureus       Year: 2020

Validity of the Stent Thrombosis Risk Score in Predicting Early Stent Thrombosis after Primary Percutaneous Coronary Intervention

Rajesh Kumar, Sahar Tariq, Madiha Fatima, Tahir Saghir, Mahesh Kumar Batra, Musa Karim, Jawaid Akbar Sial, Naveedullah Khan, Syed Nadeem Hasan Rizvi

View Abstract View Article       Journal: Journal of the Saudi Heart Association       Year: 2020

Outcome at Six Months After Primary Percutaneous Coronary Interventions Performed at a Rural Satellite Center of Sindh Province of Pakistan

Syed F. Mujtaba, Muhammad N. Khan, Hina Sohail, Jawaid A. Sial, Musa Karim, Tahir Saghir, Kiran Abbas, Moiz Ahmed, Nadeem Qamar

View Abstract View Article       Journal: Cureus       Year: 2020

Radial or femoral access in primary percutaneous coronary intervention (PCI): Does the choice matters?

Mahesh Kumar Batra, Lajpat Rai, Naveed Ullah Khan, Muhammad Naeem Mengal, Sanam Khowaja, Syed Nadeem Hassan Rizvi, Tahir Saghir, Nadeem Qamar, Jawaid Akbar Sial, Musa Karim

View Abstract View Article       Journal: Indian Heart Journal       Year: 2020

Comparative assessment of clinical profile and outcomes after primary percutaneous coronary intervention in young patients with single vs multivessel disease

Atif Sher Muhammad, Tariq Ashraf, Ayaz Mir, Syed Alishan, Faiza Farooq, Ali Ammar, Musa Karim, Syed Nadeem Hassan Rizvi, Tahir Saghir, Jawaid Akbar Sial, Naveed Ullah Khan

View Abstract View Article       Journal: World Journal of Cardiology       Year: 2020

Left Ventricular Aneurysmectomy in a Young Female of Unknown Etiology with Pseudoaneurysm: A Case Report

Tariq Ashraf, Rashid Aziz, Amin M. Khuwaja, Syed M. Afaque, Musa Karim

View Abstract View Article       Journal: Journal of the Saudi Heart Association       Year: 2020

The Frequency of Left Atrial Thrombus on Transthoracic Echocardiogram in Patients with Mitral Stenosis

Khalil Ahmed, Aziz Rehman Memon, Hussain Liaquat Sr., Mustajab Mujtaba, Chander Parkash, Fateh Ali Tipoo Sultan, Musa Karim

View Abstract View Article       Journal: Cureus       Year: 2020

Ten years risk assessment of atherosclerotic cardiovascular disease using Astro-CHARM and pooled cohort equation in a south Asian sub-population

Tariq Ashraf, Muhammad Naeem Mengal, Atif Sher Muhammad, Asal Khan Tareen, Muhammad Nauman Khan, Khawar Abbas Kazmi, Asif Nadeem, Shakil Sarwar, Zara Bashir, Nadeem Qamar, Musa Karim

View Abstract View Article       Journal: BMC Public Health       Year: 2020

Acute and sub-acute stent thrombosis: Frequency, predictors and features in patients undergoing primary percutaneous intervention at a tertiary care cardiac centre

Sahar Tariq, Rajesh Kumar, Madiha Fatima, Tahir Saghir, Sobia Masood, Musa Karim

View Abstract View Article       Journal: IJC Heart & Vasculature       Year: 2020

Conversion from Off to On-Pump Coronary Artery Bypass Grafting. Is it Avoidable?

Khuzaima Tariq, Kashif Zia, Ali Mangi, Muneer Amanullah, Pervaiz A. Chaudry, Musa Karim

View Abstract View Article       Journal: Cureus       Year: 2020

Frequency of Thrombolysis in Myocardial Infarction III Flow in Patients with Primary Percutaneous Coronary Intervention: Not All Culprit Vessels Are Completely Occluded in ST Elevation Myocardial Infarction

Muhammad Hussain, Rajesh Kumar, Ali Ammar, Syed Alishan, Atif Sher Muhammad, Fawad Farooq, Tahir Saghir, Naveedullah Khan, Syed Nadeem Hassan Rizvi, Tariq Ashraf

View Abstract View Article       Journal: Cureus       Year: 2020

Validity of TIMI Score for Predicting 14-Day Mortality of Non-ST Elevation Myocardial Infarction Patients

Dileep Kumar, Tahir Saghir, Maham Zahid, Arti Ashok, Mukesh Kumar, Arshad Ali Shah, Izza Shahid, Sajjad Ali, Ayema Haque, Musa Karim

View Abstract View Article       Journal: Cureus       Year: 2020

Comparison of Size of Pulmonary Artery and Its Branches on Transthoracic Echocardiography Versus Computed Tomographic Angiography in Patients with Tetralogy of Fallot

Shah Nawaz Sathio, Abdul S. Shaikh, Hussain Korejo, Veena Kumari, Naresh Kumar, Arshad Sohail, Mujeeb U. Rehman, Najma Patel

View Abstract View Article       Journal: Cureus       Year: 2020

Measurement of interatrial septal thickness by echocardiography in patients with moderate to severe rheumatic mitral stenosis undergoing percutaneous balloon mitral valvuloplasty

Faisal Qadir, Tariq Ashraf, Kanwal Fatima Aamir, Abdul Samad Achakzai, Syed Muhammad Afaque, Muhammad Nauman Khan, Najia Aslam Soomro, Simran Salman Qureshi, Musa Karim

View Abstract View Article       Journal: IJC Heart & Vasculature       Year: 2019

Cardiac electrophysiologic procedures — A ten years’ experience at National Institute of Cardiovascular Diseases, Karachi

Sajid Ali Shaikh, Syed Zahid Jamal, Faisal Qadir, Zubair Mumtaz, Zia Ullah, Abdul Mueed, Musa Karim, Ghazala Irfan

View Abstract View Article       Journal: The Journal of the Pakistan Medical Association       Year: 2019

Performance of the TIMI risk score in predicting mortality after primary percutaneous coronary intervention in elderly women: Results from a developing country

Shumaila Furnaz, Musa Karim, Tariq Ashraf, Sajjad Ali, Izza Shahid, Sara Ali, Uzzam Ahmed Khawaja, Muhammad Tanzeel ul Haque, Muhammad Shariq Usman, Tariq Jamal Siddiqi

View Abstract View Article       Journal: PLoS ONE       Year: 2019

Evaluating the knowledge of Endotracheal Cuff pressure monitoring among critical care providers by palpation of pilot balloon and by endotracheal tube cuff manometer

Jawed Abubaker, Ziaullah Syed, Shazia Ahmed, Aziz-Ur-Rehman Memon, Zohaib Jawed Abubaker, Muhammad Imran Ansari, Musa Karim

View Abstract View Article       Journal: Cureus       Year: 2019

Patterns in Risk Factors of Cardiovascular Disease using the Apriori Algorithm

Musa Karim, Shumaila Furnaz, Tahir Saghir, Nadeem Hasan Rizvi, Ahmed Raheem

View Abstract View Article       Journal: International Journal of Cardiovascular Research       Year: 2019

Site of Central Venous Access Not Important for Fluid Resuscitation and Monitoring

Muhammad Imran Ansari, Jawed Abubaker, Syed Zia Ullah, Adeel Sohail, Aziz Ur Rehman, Shazia Ahmad, Musa Karim

View Abstract View Article       Journal: Pakistan Armed Forces Medical Journal       Year: 2019

Correlation between Gensini Score and Duration of Diabetes in Patients Undergoing Coronary Angiography

Razi Ul Amin, Muhammad Anis M. Ahmedani , Musa Karim, Ahmed Raheem

View Abstract View Article       Journal: Cureus       Year: 2019

New-onset Atrial Fibrillation in Patients Presenting with Acute Myocardial Infarction

Zafar Iqbal, Muhammad Naeem Mengal, Abida Badini, Musa Karim

View Abstract View Article       Journal: Cureus       Year: 2019

Incidence of Aortic Regurgitation in Association with Type of Ventricular Septal Defects and its Immediate and Intermediate Outcome after Surgical Closure

Veena Kumari, Abdul Sattar Shaikh, Saad Bader, Naresh Kumar, Sohail Khan Bangash, Najma Patel

View Abstract View Article       Journal: Cureus       Year: 2019

Evaluation of Contrast Amount in Patients Undergoing Cardiac Catheterization for Diagnostic and Therapeutic Procedures

Syed Fayaz Mujtaba, Tahir Saghir, Jawaid Akbar Sial, Khalid Nasseb, Musa Karim

View Abstract View Article       Journal: EC Cardiology       Year: 2019

Procedural determinants of fluoroscopy time in patients undergoing cardiac catheterization

Syed Fayaz Mujtaba, Tahir Saghir, Jawaid Akbar Sial, Nadeem Hassan Rizvi

View Abstract View Article       Journal: Pakistan Journal of Medical Sciences       Year: 2019

Perceptions and Practices towards Medication Non-Adherence among Hypertensive Patients: An Observational Study

Muhammad N. Khan, Najia Soomro, Tariq Ashraf, Khalid Naseeb, Rajesh Kumar, Usman Bhatti, Syed Taha Ali, Musa Karim

View Abstract View Article       Journal: Cureus       Year: 2019

Impact of Temperature Variation on Acute Myocardial Infarction in Karachi, Pakistan

Sanam Khowaja, Musa Karim, Maham Zahid, Annam Zahid, Salik Ahmed, Khawar Kazmi, Syed Z. Jamal

View Abstract View Article       Journal: Cureus       Year: 2019

Angiographic characteristics and in hospital outcome of young patients, age up to 40 versus more than 40 years undergoing primary percutaneous coronary intervention

Mahesh Kumar Batra, Nadeem Hasan Rizvi, Jawaid Akbar Sial, Tahir Saghir, Musa Karim

View Abstract View Article       Journal: Journal of the Pakistan Medical Association       Year: 2019

Initial Experience of Transthoracic Echocardiography at a Newly Operational Satellite Center in Hyderabad, Pakistan

Iram J. Balouch, Nadeem Qamar, Lubna Baqai, Mariam Naz, Sumyia Gurmani, Musa Karim

View Abstract View Article       Journal: Cureus       Year: 2019

Initial Experience of Minimally Invasive Concomitant Aortic and Mitral Valve Replacement/Repair at a Tertiary Care Cardiac Centre of a Developing Country

Kashif Zia, Ali R. Mangi, Hafeezullah Bughio, Khuzaima Tariq, Pervaiz A. Chaudry, Musa Karim

View Abstract View Article       Journal: Cureus       Year: 2019

Correlation between Echocardiography and Cardiac Catheterization for the Assessment of Pulmonary Hypertension in Pediatric Patients

Arshad Sohail, Hussain B. Korejo, Abdul Sattar Shaikh, Aliya Ahsan, Ram Chand, Najma Patel, Musa Karim

View Abstract View Article       Journal: Cureus       Year: 2019

Clinical, Angiographic Characteristics and In-Hospital Outcomes of Smoker and Nonsmoker Patients After Primary Percutaneous Coronary Intervention

Tariq Ashraf, Syed Muhammad Afaque, Rashid Aziz, Muhammad Nauman Khan, Abdul Samad Achakzai, Alizay Lateef, Musa Karim, Tahir Saghir, Syed Nadeem Hassan Rizvi, Syed Ishtiaq Rasool

View Abstract View Article       Journal: Global Heart       Year: 2019

Clinical and procedural predictors and short-term survival of the patients with no reflow phenomenon after primary percutaneous coronary intervention

Tariq Ashraf, Muhammad Nauman Khan, Syed Muhammad Afaque, Kanwal Fatima Aamir, Mukesh Kumar, Tahir Saghir, Syed Ishtiaq Rasool, Syed Nadeem Hassan Rizvi, Jawaid Akbar Sial, Asif Nadeem, Abid Amin Khan, Musa Karim

View Abstract View Article       Journal: International Journal of Cardiology       Year: 2019

Assessment of electrocardiographic criteria of left atrial enlargement

Mahesh Kumar Batra, Atif Khan, Fawad Farooq, Tariq Masood, Musa Karim

View Abstract View Article       Journal: Asian Cardiovascular and Thoracic Annals       Year: 2018

Risk Factors of Atrial Fibrillation in Patients with Heart Failure

Alam Sarfraz, Parveen Akhtar, Syed N. Hassan Rizvi, Musa Karim

View Abstract View Article       Journal: Cureus       Year: 2018

Assessment of Femoral Artery Bifurcation Level with Conventional Angiography

Muhammad N Mengal, Tariq Ashraf, Syed N Hassan Rizvi, Abida Badini, Musa Karim

View Abstract View Article       Journal: Cureus       Year: 2018

Contrast-Induced Acute Kidney Injury: The Sin of Primary Percutaneous Coronary Intervention

Mahesh Kumar Batra, Jawaid Akbar Sial, Rajesh Kumar, Tahir Saghir, Musa Karim, Nadeem Hasan Rizvi, Nadeem Qamar

View Abstract View Article       Journal: Pakistan Heart Journal       Year: 2018

Severity of Coronary Artery Disease in Non-ST Elevation Myocardial Infarction (NSTEMI) Patients with High Troponin-I Level

Sajid Ali Shaikh, Ghulam Abbas Shaikh, Musa Karim

View Abstract View Article       Journal: Pakistan Heart Journal       Year: 2018

Multivessel Disease As A Prognostic Marker In Patients Presenting For Primary Percutaneous Coronary Intervention

Mahesh Kumar Batra, Syed Ishtiaq Rasool, Bashir Ahmed Solangi, Naveedullah Khan, Musa Karim, Syed Nadeem Hassan Rizvi

View Abstract View Article       Journal: Journal of Ayub Medical College Abbottabad       Year: 2018

Echocardiography guided bed side balloon atrial septostomy in dextro transposed great arteries (dTGA) with intact ventricular septum (IVS): A resource limited country experience

Naresh Kumar, Abdul Sattar Shaikh, Veena Kumari, Najma Patel

View Abstract View Article       Journal: Pakistan journal of medical sciences       Year: 2018

Medication Non-Adherence in Post Myocardial Infarction Patients

Saba Hussain, Syed Zahid Jamal, Faisal Qadir

View Abstract View Article       Journal: Journal of Ayub Medical College Abbottabad       Year: 2018

Risk of thromboembolism in non-valvular atrial fibrillation and adequacy of anticoagulation in high risk patients

Fawad Farooq, Muhammad Hashim, Muhammad Rahman Khalid, Musa Karim

View Abstract View Article       Journal: Pakistan Heart Journal       Year: 2018

Assessment of Femoral Artery Bifurcation Level with Conventional Angiography

Muhammad Naeem Mengal, Tariq Ashraf, Syed N. Hassan Rizvi, Abida Badini, Musa Karim

View Abstract View Article       Journal: Cureus       Year: 2018

Comparison of Radiation and Contrast Safety between Radial and Femoral Approaches in Patients Undergoing Coronary Catheterization

Sayed Fayaz Mujtaba, Tahir Saghir, Khalid Naseeb, Jawaid Akbar, Sial Nadeem H Rizvi

View Abstract View Article       Journal: Pakistan Heart Journal       Year: 2018

Use of Novel oral anticoagulants (NOACs) in patients with risk of stroke in non valvular Atrial Fibrillation (AF)

Fawad Farooq, Muhammad Hashim, Musa Karim, Ali Yasir

View Abstract View Article       Journal: International Journal of Endorsing Health Science Research       Year: 2017


Email: research@nicvd.org

Phone: 021-99201271-5 Ext: 432